Partner 7

Research Institute for Chemistry – Bucharest


Biotechnology Department

202 Spl. Independentei, 77208 Bucharest, ROMANIA

Tel. 00-402-12248800; Fax. 00-402-3123493

Representative: Dr. Mihaela BADEA, Senior scientist II

General activity

ICECHIM is one of the main institutes from Romania in the field of chemistry. The scientific activity of the institute is based on: development of studies and projects, prognosis and chemical engeneering in biotechnology, chemistry & petrochemistry; research & technical control for laboratory, pilot plants, semi-industrial and industrial chemical & petrochemical installations; development of original technologies for synthesis of surfactants & detergents, polymeric plastics & composites, elastomers, pesticides, dyes & pigments, synthetic fibres.

The Biotechnology Department is composed by 5 laboratories: Biochemistry Lab, Microbiology Lab, Bioreactors Lab, Lab of biologic-active compounds extraction and (Ligno)cellulosic bio-treatment Lab.

Research Activity

In the Biotechnology Department are developed the following main research activities:

The research activity is financed by national and international programmes & grants and by the industrial partners which are direct beneficiaries of the research results.

Training Activity

The Biotechnology Department has strong links with:

for the next training activities: organising of laboratory practices for students in field of biochemistry, biotechnology, biophysics and analytical chemistry; hosting of students for Disertation Thesis preparation for B.Sc. and M.Sc. Degrees; hosting of Ph.D. students.

The Biotechnology Department is partner in another Leonardo da Vinci Pilot Project: "Eurocompetencies Transfer in Vocational Guidance for Young Specialists in Bioscience Field", Contract nr. RO/OO/B/F/PP141028.

List of publications(selection)

A flow immunoassay for alkyphenol ethoxylate surfactants and their metabolites questions associated with cross-reactivity, matrix effects and validation by chromatographic techniques. M. Badea, C. Nistor, Y. Goda, S. Fujimoto, S. Dosho, A. Danet, D. Barceló, F. Ventura, and J. Emnéus., Analyst, 128, 849 – 856 (2003)

Entrapment of protease into silica gel matrix, M. Răileanu, L. Stanciu, C. Pârlog, D. L. Bordeianu, M. D. Stănescu, M. Badea, Revue Roumaine de Chimie, 47(6), 533-538 (2002)

Amperometric method based on acetylcholinesterase inhibition for paraoxon determination. M. Badea, A.F. Danet, S. Serban, Rev. Chim., 51(7), p. 481-486 (2000)

Solid state fermentation of agricultural wastes for endoglucanase production. L. Jecu, Inds.Crops Prod., Elsevier Sci. 11, 1-5 (2000)

Effects of Solubulization Process in AOT-Isooctane Reverse Micelles on the Catalytic Activity of Alcohol Oxidase from Hansenula polymorpha. I. Influence of Reaction Medium on Alocohol Oxidase Activity During the Process of Solubilization in Reverse Micelles, M.L. Arsene, Progress in Catalysis, 8, 61-64 (1999)

Effects of Solubulization Process in AOT-Isooctane reverse Micelles on the Catalytic Activity of Alcohol Oxidase from Hansenula polymorpha. II. The Relationship Between Catalytic Activity of Alcohol Oxidase Solubilized in Reverse Micelles and the Microstructured Media. M.L. Arsene, Progress in Catalysis , 8, 65-69 (1999)

Reverse Micelles as a Potential reaction Medium for Alcohol Oxidase Application in Biotransformation M.L. Arsene, I. F.Dumitru , S. Niculescu, Roum.Biotechnol.Lett., 4(2), p.35-39 (1998 )

The effects of phenolic compounds on the growth and activity of hydrolytic enzymes at Aspergillus niger, L. Jecu, Rev.Rom.Biochim., 34 (1-2), 99-102 (1998)

Catalytic Properties of AO to oxidize aliphatic and aromatic alcohols. M. Badea, M.L. Arsene, Progress in Catalysis, 5(1), p. 45-50 (1996)